Mark Mercola, Ph.D. - November 27, 7-8 p.m., Rockwell Pavilion, UH M.D. Anderson Library
“Regenerating Damaged Heart Muscle: Using Stem Cells and Systems Biology to Discover Drug Targets”
In the U.S., chronic heart failure has a 10% annual mortality rate and approximately 50% mortality after 5 years. It affects 5.4 million people, with 690,000 new cases each year. Although current medical care has improved survival, therapies do not treat the underlying cause – which is death or damage of heart muscle cells combined with increased scarring and loss of contractile function. As a result, heart failure progresses. Therapies with the potential to reverse disease progression are needed. Recent studies point to a small number of stem cells capable of regeneration. Dr. Mercola’s research focuses on understanding the mechanisms of regeneration. The lab is developing small molecule and RNA-based pharmacological approaches to promote regeneration and improve the function of the damaged heart.
Mark Mercola, Ph.D.
Professor and Director, Muscle Development and Regeneration Program
Sanford-Burnham Medical Research Institute
Dr. Mark Mercola is professor and director of the Muscle Development and Regeneration Program at the Sanford-Burnham Medical Research Institute and holds adjunct professorships in the Departments of Pathology and Pediatrics at the University of California, San Diego.