Bruce M. Spiegelman, Ph.D. - April 25

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“Toward a New Generation of Therapies for Diabetes, Obesity and Muscular Disease”

We are experiencing a worldwide epidemic of obesity and type II diabetes. Dr. Spiegelman will discuss his research team’s recent discovery of a novel hormone secreted from muscle cells that triggers some of the key health benefits of exercise. The protein, given the name irisin, is a promising candidate for development as a novel treatment for diabetes, obesity and perhaps other disorders.


Bruce M. Spiegelman, Ph.D.
Stanley J. Korsmeyer Professor of Cell Biology and Medicine
Dana-Farber Cancer Institute, Harvard Medical School

Bruce M. Spiegelman is the Stanley J. Korsmeyer Professor of Cell Biology and Medicine at Harvard Medical School and Dana-Farber Cancer Institute. Dr. Spiegelman received a B.S. with highest honors from the College of William and Mary in 1974, his Ph.D. in biochemistry from Princeton University in 1978, and completed postdoctoral work at Massachusetts Institute of Technology. He joined Harvard Medical School and Dana-Farber Cancer Institute in 1982.

His research focuses on fat cell biology, diabetes and muscular diseases. Dr. Spiegelman has been honored with many awards including the Bristol-Myers Squibb Award for Distinguished Achievement in Metabolic Research; the Solomon Berson Award from the American Physiological Society; the Rolf Luft Award in Endocrinology from the Karolinska Institute (Sweden); the Trans-Atlantic Medal, British Endocrine Society; the Naomi Berrie Award for Outstanding Achievement in Diabetes Research, Columbia University; and the American Diabetes Association’s 2012 Banting Medal for Scientific Achievement.

In 2002, Dr. Spiegelman was elected to the American Academy of Arts and Sciences and the National Academy of Sciences.